Lecture: Network motifs

Cellular processes are fine-tuned by complex regulations e.g. signaling pathways, the transcription network, and circuits for cell cycle control, the regulation of growth or stress response. Signaling systems can be described as a network, with nodes representing biochemical substances or complexes (sometimes in different modifications). During the lecture we will talk about the topological properties of such a network. We will also discuss the biological relevance of a common network structures, called network motifs. In this lecture we will focus on negative feedback motif.

FILES: slides